O Δρ Τάσος Βαρθολομαίος είναι  Ιατρός Ιστοπαθολόγος-Ομοιοπαθητικός, τ.Επιμελητης ΕΣΥ,Μέλος της ΔΙΕΘΝΟΥΣ ΕΤΑΙΡΕΙΑΣ ΕΦΑΡΜΟΓΗΣ ΤΗΣ ΟΜΟΙΟΠΑΘΗΤΙΚΗΣ  ΣΤΗΝ ΟΓΚΟΛΟΓΙΑ .Η πολυετης κλινική του εμπειρία στην Παθολογία του Καρκίνου ως Ιστοπαθολόγος είναι η ασφαλής βάση για την πλέον κατάλληλη εφαρμογή της Ομοιοπαθητικής σε κάθε μία  ξεχωριστή περίπτωση.

για να κλείσετε  ΟΜΟΙΟΠΑΘΗΤΙΚΗ ΣΥΝΕΝΤΕΥΞΗ 
επικοινωνείστε με
τηλ:   6932907696
e-mail:  pathan@otenet.gr

Η Ιπποκρατική Ιατρική θεωρεί ότι ο καρκίνος είναι μια συστηματική ασθένεια, δηλαδή μια ασθένεια που επηρεάζει ολόκληρο το σώμα, και όχι μόνο ένα συγκεκριμένο όργανο, και οτι η θεραπεία του καρκίνου μπορεί να επιτευχθεί με την εξισορρόπηση ολόκληρου του οργανισμού και όχι μόνο με την εξάλειψη του όγκου.Σύμφωνα με μια πρόσφατη δημοσίευση με τίτλο «Μαθήματα από τον Ιπποκράτη: Ώρα να αλλάξουμε το παράδειγμα του καρκίνου» το τρέχον μοντελο  θεραπείας του καρκίνου πρέπει να προσαρμοσθεί στην Ιπποκρατικη Αντίληψη.Το το νέο μοντέλο πρέπει να αντικατοπτρίζει ότι ο καρκίνος είναι μια συστηματική ασθένεια, η οποία επηρεάζει έναν συγκεκριμενο ασθενή και όχι μια απλή ομάδα μεταλλαγμένων κυττάρων που πρέπει να εκριζωθούν. (Galmarini, 2020).

Για την πλήρη λήψη ιστορικού των καρκινοπαθών, η συμβατική προσέγγιση θα πρεπει να αναβαθμιστεί από το Ιπποκρατικό Ιατρικό μοντέλο. Σε ένα πλήρες ιστορικό,το σύνολο των κύριων και δευτερογενών προβλημάτων υγείας συνθέτουν ένα μοναδικό Κλινικοπαθολογικό Σύνδρομο (CPS), το οποίο είναι το κλειδί για την κατανόηση της κατάστασης της υγείας του ασθενούς, για έναν πιο αποτελεσματικό σχεδιασμό της θεραπείας και της βελτιωσης της πρόγνωσης της νόσου.Οι συνακόλουθες ψυχικές και συναισθηματικές εμπειρίες των καρκινοπαθών είναι συχνά αυτές της απόσυρσης και της κατάθλιψης. Χωρίς να λαμβάνεται υπόψη η ψυχοσωματική του καρκίνου, δεν μπορεί κανείς ποτέ να κατανοήσει ολόκληρη τη σειρά των φαινομένων στις περισσότερες περιπτώσεις καρκίνου, έτσι ώστε η ψυχική αξιολόγηση των καρκινοπαθών θα πρέπει να ενσωματωθεί στη κατανόηση και αντιμετωπιση του καρκίνου, χρησιμοποιώντας όλα τα σύγχρονα δεδομένα της ψυχο-ογκολογίας.Η θεραπευτική αντιμετώπιση θα πρέπει επίσης να λάβει υπόψη το γεγονός ότι η μεγάλη πλειονότητα των μεταστάσεων αφορα τέσσερα όργανα: μυελό των οστών, εγκέφαλο, πνεύμονες και ήπαρ,και θα πρέπει να περιλαμβάνει τα κατάλληλα μέσα που θα μπορούσαν να διατηρήσουν ή να αποκαταστήσουν τη φυσιολογία αυτών των οργάνων.

Ο Δρ Τάσος Βαρθολομαίος εχει αναπτύξει  ιδιαίτερα την αξιοποίηση όλων των κλινικοπαθολογικών δεδομένων για τον πλέον κατάλληλο σχεδιασμό της ομοιοπαθητικής αγωγής σε κάθε μια περίπτωση πάσχοντος απο καρκίνο.
 
O ρόλος της Ομοιοπαθητικής στον Καρκίνο  είναι :
η ενίσχυση των μηχανισμών άμυνας του οργανισμού σύμφωνα με τα σύγχρονα δεδομένα της ανοσολογίας,
η υποβοήθηση των ομοιοστατικών μηχανισμών σύμφωνα με τα σύγχρονα δεδομένα της παθολογικής φυσιολογίας,
η ψυχοσωματική στήριξη των ασθενών σύμφωνα με τα σύγχρονα δεδομένα της ψυχο-ογκολογίας
και το ΣΗΜΑΝΤΙΚΟΤΕΡΟ
η εξυγίανση του μικροπεριβάλλοντος των κυττάρων.Το μικροπεριβάλλον των  κυττάρων (Matrix)  σήμερα θεωρείται απο την Κλασσική Έρευνα του Καρκίνου  σημαντικός παράγων για την ανάπτυξη καρκινικών κυττάρων  και για την επέκταση τους τοπικά ή και σε όλο τον οργανισμό

Ο Δρ Τάσος Βαρθολομαίος  είναι Ιατρός Ιστοπαθολόγος ,με μετεκπαιδευση στην Παθολογία του Καρκίνου στο Θεαγένειο Αντικαρκινικο Νοσοκομειο Θεσσαλονικης και σε Πανεπιστημικα Νοσοκομεια στην Οξφόρδη,Διδάκτωρ Ιατρικής, με πολυετή προϋπηρεσία στο Εθνικό Σύστημα Υγείας,κάτοχος του Διπλώματος (DIHom) και  του  Μεταπτυχιακού Διπλώματος (ΗMD) Ομοιοπαθητικής Ιατρικής  στη Μ.Βρετανία ,Τακτικό Μέλος τής Βρετανικής Εταιρείας  Ομοιοπαθητικής  Ιατρικής (MFHom) ,Ανώτατος Τιτλος που αποκτάται μετα απο την ολοκλήρωση μιάς προηγμένου επιπέδου Ομοιοπαθητικής Εκπαίδευσης και  εξετάσεις επιπεδου Ιατρικής Ειδικότητας
 

Σε όλες τις παθήσεις η ομοιοπαθητική συνταγογράφηση διαμορφώνεται με βάση την κλινικά προσανατολισμένη Ομοιοπαθητική και το γνωστικό περιεχόμενο της ιατρικής ειδικοτητας του Δρ Τάσου Βαρθολομαίου,η οποία παίζει σημαντικό ρόλο στον σχεδιασμό της ιατρικής αντιμετώπισης του καρκίνου .Η ειδικότητα αυτή ασχολείται πρωτιστα με τις βασικές πτυχές ολων των παθήσεων,από το πώς αναπτύσσονται ως τη διάγνωση και τον προσδιορισμό όλων των χαρακτηριστικών τους, τα οποία καθορίζουν την ενδεικνυόμενη θεραπεία τους.Iδιαιτερη είναι η συμβολή της Ιατρικής Ειδικότητας του Δρ Τασου Βαρθολομαίου στην αντιμετώπιση του ΚΑΡΚΙΝΟΥ με την έγκαιρη διάγνωση, την αναγνώριση των αιτίων και της παθογένειας του καρκινου σε κάθε ασθενή, την πρόγνωση και την ενδεικνυόμενη θεραπευτική αντιμέτωπιση
 

Η ιατρικά προσανατολισμένη Ομοιοπαθητική, « για την ΑΣΘΕΝΕΙΑ και τον ασθενή», είναι η κατεξοχήν θεραπευτική η οποία είναι ευθυγραμμισμενη και άρρηκτα συνδεδεμενη με την Ιατρική Φυσιολογία, την Παθολογική Φυσιολογία και την Παθολογία (Pathology), όπως αυτές διδάσκονται στις Ιατρικές Σχολές και όπως πρέπει να αποτελούν το θεμέλιο ολων των ιατρικών εφαρμογών.Με αυτή τη βάση χρησιμοποιεί μια εμπεριστατωμένη Φαρμακολογία, με φάρμακα τα οποία δρουν εκλεκτικά,το καθένα,σε συγκεκριμένα όργανα,ιστούς,κύτταρα  και σε συγκεκριμένες λειτουργικές διαδικασίες.Η Φαρμακολογία αυτή απέδειξε ήδη την αξία της σε επίπεδο όχι μονον Πρωτοβάθμιας Υγείας αλλά και σε επίπεδο Δευτεροβάθμιας Υγείας, δηλαδη σε Κρατικά Νοσοκομεία σε πολλες χώρες του κοσμου από τα τελη του 19ου αιωνα μεχρι σήμερα. Με βαση αυτή την επιστημονική λογική μπορεί να συνυπαρχει με όποια άλλη επιστημονικά τεκμηριωμένη ιατρική διαδικασία και αποτελεί, εξ αντικειμένου,  ένα  πολύτιμο συστατικό στοιχείο της Κλασσικής Δυτικής Ιατρικής.

Η κλινικά προσανατολισμένη Ομοιοπαθητική Φαρμακολογία έχει τη δυνατότητα να απευθύνεται στοχευμένα σε ολους τους μηχανισμούς που υπεισερχονται στην παθογένεια και εξέλιξη των χρόνιων παθήσεων και να επηρεάζει ουσιαστικά και θετικά την πρόγνωση και την πορεία της νόσου και της συνολικής υγείας του ασθενούς.Ο Δρ Τάσος Βαρθολομαίος έχει αναπτύξει ιδιαίτερα αυτό το κεφάλαιο της Ομοιοπαθητικής Φαρμακολογίας , εφαρμόζοντας την Ομοιοπαθητική παράλληλα με όποια συμβατική Ογκολογική θεραπεία (χειρουργικη, φαρμακευτική, κτλ) ακολουθούν ήδη  οι ασθενείς απο τον Ειδικό Ογκολόγο .Σε κάθε περίπτωση ,γίνεται εμπεριστατωμένη μελέτη τόσο των Εργαστηριακών εξετάσεων όσο και του πλήρους ιστορικού για τη διερεύνηση και αποσαφήνιση των αιτίων και της παθογένειας της ανάπτυξης της Χρόνιας Πάθησης σε κάθε μια ξεχωριστή περίπτωση. Ως ΙΑΤΡΟΣ ΙΣΤΟΠΑΘΟΛΟΓΟΣ (ΠΑΘΟΛΟΓΟΑΝΑΤΟΜΟΣ) ,ο Δρ Τάσος Βαρθολομαίος μπορεί επιπλέον να σας δώσει τη Συμβουλή του πάνω στις ΙΣΤΟΛΟΓΙΚΕΣ (ΠΑΘΟΛΟΓΟΑΝΑΤΟΜΙΚΕΣ) ΕΞΕΤΑΣΕΙΣ που εχουν γίνει , σε συνδυασμό με το Κλινικό Ιατρικό και το Ομοιοπαθητικό ιστορικό και τους λοιπους Κλινικο-Εργαστηριακούς Ελέγχους.

Online video consultations

ΙΑΤΡΙΚΗ BΙΒΛΙΟΓΡΑΦΙΑ για τον ΚΑΡΚΙΝΟ:

Hahnemann,S.1988.”The Chronic Diseases”.New Delhi: B.Jain Publishers Pvt.Ltd.

Hall,EJ.2000.Radiobiology for the radiologist.Philadelphia: Lippincott Williams Wilkins. p. 351 .

Hanoun,M,Maryanovich,M,Arnal-Estapé,A,Frenette,PS.2015.”Neural regulation of hematopoiesis, inflammation, and cancer”. Neuron.86(2):360-373.

Hanselmann,RG,and Welter,C.2016.“Origin of Cancer:An Information, Energy, and Matter Disease”. Front Cell Dev Biol 4:121.

Harris ,A.2001.” Hypoxia — a key regulatory factor in tumour growth”. Nature Rev. Cancer 2: 38–47.

Haruki,T,Nakamura,H,Taniguchi,Y.2010.”Spontaneous regression of lung adenocarcinoma: Report of a case”.Surg Today 40(12):1155-1158.

Hauer-Jensen,M, Denham,JW, Andreyev,HJ.2014.”Radiation enteropathy-pathogenesis,treatment and prevention”.Nature Reviews. Gastroenterology & Hepatology 11 (8): 470–479.

Helbig,D, Quesada,AE, Xiao,W, Roshal,M, Tallman,MS, Knorr,DA.2020.
“Spontaneous Remission in a Patient With Acute Myeloid Leukemia Leading to Undetectable Minimal Residual Disease”. J Hematol.9(1-2):18-22.

Heng,J et al.2014.“Solar elastosis in its papular form: uncommon, mistakable”. Case reports in dermatology vol. 6,1:124-8.

Henry,M and Schwartz,L.2019. “Entropy export as the driving force of evolution”. Substantia, 29-56.

Henson,CC,Burden,S,Davidson,SE,Lal,S.2013."Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy". The Cochrane Database of Systematic Reviews (11): CD009896.

Hernández,LG, van Steeg, H, Luijten, M, van Benthem, J.2009.” Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach”. Mutat Res. 682(2-3):94-109.

Herrera-Heredia,SA,Hsu,HP, Kao, CY, et al. 2022.”Heparin is required for the formation of granules in connective tissue mast cells”.Front Immunol.13:1000405.

Heyes,H,Glück,D.1977.” Die Bedeutung des Fibrins/fibrinogens für Wachstum und Metastasierung von Malignomen [The significance of fibrin/fibrinogen for growth and metastasis of malignant tumors (author's transl)]”. Klin Wochenschr. 55(22):1079-1087.

Ho Sang,L, Dae Young,C,Jin Il,K,Se Hyun,C,Soo-Heon,P, Joon-Yeol,H and Jae Kwang,K.2010.”A Case of Spontaneous Regression of Advanced Gastric Cancer”.J Korean Med Sci.25(10):1518-1521.

Hockel,M,and Vaupel,P.2001.”Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects”. J Natl Cancer Inst.93:266–276.

Holly,JM et al.2013.“Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?”.Cancer metastasis reviews vol. 32,3-4: 673-705.

Hong,Y,Fang,F,Zhang,Q.2016."Circulating tumor cell clusters: What we know and what we expect (Review)". International Journal of Oncology 49, no. 6: 2206-2216.

Hood, JD, Cheresh, DA. 2002.”Role of integrins in cell invasion and migration”. Natl Rev Cancer 2:91–100.
Hoption,C,van Netten,JP,van Netten,C, Glover,DW.2002.”Spontaneous regression:a hidden treasure buried in time”.Med Hypotheses.58(2):115-119.

Hoskin,DH, Mader, JS, Furlong, SJ, Conrad, DM, Blay, J.2008.” Inhibition of T-cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review)”. Int J Oncol.18:527–535.
Houzelle,A, et al.2021.”Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity”.Diabetologia 64:424–436.

Howley, PM.2015. “Gordon Wilson Lecture: Infectious Disease Causes of Cancer: Opportunities for Prevention and Treatment.” Transactions of the American Clinical and Climatological Association vol. 126 : 117-32.

Hoye,A and Erler,J.2016.”Structural ECM components in the premetastatic and metastatic niche”.American Journal of Physiology/Cell Physiology 310(11):955-967.

Hoye,A and Erler,J.2016.”Structural ECM components in the premetastatic and metastatic niche”.Journal of the American Physiological Society.Cell Physiology Vol 310 Issue 11016: C955-C967.

Huang,L, Bindra,R, Glazer,P, Harris,A.2007.”Hypoxia-Induced Genetic Instability - a Calculated Mechanism Underlying Tumor Progression”. Journal of Molecular Medicine 85(2) 139-148.

Huang,S,Li,JY,Wu,J,Meng,L,Shou,CC.2001.”Mycoplasma infections and different human carcinomas” .World J Gastroenterology 7(2): 266-269.

Huang, TW, Chen, YL, Chen, JC, Tsai, WC, Chang, H, Lee, SC.2009.” Spontaneous regression of a mediastinal thymoma”. J Thorac Cardiovasc Surg.137:1277–1278.
Huiwen,L, Ying, L, Rihan, H, Weihua,L,Xiangjian,L.2023.”The role of circadian clocks in cancer: Mechanisms and clinical implications”.Genes & Diseases Volume 10, Issue 4: 1279-1290.

Høye,AM,and Erler,JT. 2016. ”Structural ECM components in the premetastatic and metastatic niche”.Am J Physiol Cell Physiol. 310(11):C955-C967.

Huz,JI, Melis,M, Sarpel,U.2012.” Spontaneous regression of hepatocellular carcinoma is most often associated with tumor hypoxia or a systemic inflammatory response”. HPB(oxford) 14: 500-505.

Iakovidis,V and Iakovidis, A.2001. Αρχές Ψυχοογκολογίας (Principles of Psycho-Oncology).Thessaloniki:Mastorides Publications.

Iddamalgoda ,A, Le, QT, Ito, K, Tanaka, K, Kojima,H, Kido,H.2008.”Mast cell tryptase and photoaging: possible involvement in the degradation of extra cellular matrix and basement membrane proteins”.Arch Dermatol Res.300 Suppl 1:S69-S76.

Ikuta,S,Miki,C,Ookura,E,Tonouchi H, Kusunoki M.2002.”Spontaneous regression of a metastatic liver tumor: report of a case”.Surg Today. 32(9):844-848.

Imyanitov,EN et al.2023.“Hereditary cancer syndromes”. World journal of clinical oncology vol. 14,2 : 40-68.

Ingber,DE.2008.”Can cancer be reversed by engineering the tumor microenvironment?”.Semin Cancer Biol.18(5):356-364.

International Commission on Radiological Protection, Recommendations: ICRP Publication No. 60 (New York: Pergamon Press, 1991), cited in Hall, Radiobiology for the Radiologist, 4th ed., 456.

Ishihara,M,Yamamoto,K, Miwa,H,Nishi,M.2017.”Spontaneous complete regression of a brain stem glioma pathologically diagnosed as a high-grade glioma”.Childs Nerv Syst.33(12):2177-2180.

Ito, E, Nakano, S, Otsuka, M.2016.” Spontaneous breast cancer remission: A case report”. Int J Surg Case Rep. 25:132-136.

Iuliano,M, Santilli,V, Mineo,A.2024.”Inflammatory Response Modulation by Low-Dose Anti-inflammatory Drugs Treatment in an In Vitro Osteoarthritis Cellular Model”.Curr Med Chem.31(13):1740-1753.

Jain, RK.2013.“Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers”. Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 31,17 : 2205-18.

Jakoube,P et al.2021. “Mitochondrial Tumor Suppressors-The Energetic Enemies of Tumor Progression”.Cancer research vol. 81,18 : 4652-4667.

Janecka,I.2007.“Cancer control through principles of systems science, complexity, and chaos theory: a model”.International journal of medical sciences vol. 4,3:164-73.

Janet S. Butel.2000.”Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease”.Carcinogenesis,Volume 21, Issue 3: 405–426.

Jang,YY,Collector,MI,Baylin,S,Diehl,A,Sharkis,S.2004.”J. Hematopoietic stem cells convert into liver cells within days without fusion”. Nat. Cell Biol. 6, 532–539 .

Janiszewska,AD,Poletajew,S,Wasiutynski,A.2013.”Spontaneous regression of renal cell carcinoma”. Vol. 17, Wspolczesna Onkologia p. 123–7.
Javid,H et al.2023.“The role of viruses in cancer development versus cancer therapy: An oncological perspective”.Cancer medicine vol. 12,10: 11127-11148.

Jensen,LD.2014.”The circadian clock and hypoxia in tumor cell de-differentiation and metastasis”. Biochim Biophys Acta 1850(8):1633-1641.

Jin,J et al.2021.“The Structure and Function of the Glycocalyx and Its Connection With Blood-Brain Barrier”. Frontiers in cellular neuroscience vol. 15 739699.

Joensuu,H.2008."Systemic chemotherapy for cancer: from weapon to treatment". The Lancet. Oncology. 9 (3): 304.

Kaestner,SA, Sewell, GJ.2007. "Chemotherapy dosing part I: scientific basis for current practice and use of body surface area". Clinical Oncology. 19 (1): 23–37.

Kakuta,N Yasumoto,T,Yoshida,Y..2022.”Spontaneous regression of lung metastases after transarterial chemoembolization for hepatocellular carcinoma”. Radiol Case Rep.17(12):4934.

Kaldate,RR, Haregewoin, A, Grier, CE, Hamilton,SA, McLeod, HL.2012. ”Modelling the 5-fluorouracil area under the curve versus dose relationship to develop a pharmakokinetik dosing algorithm for colorectal cancer patients receiving FOLFOX6”. The Oncologist 17 (3): 296–302.

Kamran,SC, Berrington de Gonzalez,A, Ng,A, Haas-Kogan,D, Viswanathan,AN. 2016. "Therapeutic radiation and the potential risk of second malignancies". Cancer. 122 (12): 1809–1821.

Kaplan,RN,Psaila,B,Lyden,D.2006.”Bone marrow cells in the 'pre-metastatic “niche” within bone and beyond”.Cancer Metastasis Rev. 25(4):521-529.

Kappauf,H,Gallmeier,WM,Wunsch,PH.1997.” Complete spontaneous remission in a patient with metastatic non-small-cell lung cancer: case report, review of literature, and discussion of possible biological pathways involved”. Ann Oncol. 8:1031-1039.

Karlin,S,and Cambell,AM.1994.”Which bacterium is the ancestor of the animal mitochondrial genome?”.Proc. Natl. Acad. Sci. USA Vol. 91, pp. 12842-12846.

Katano,A, Takenaka,R, Okuma,K, Yamashita, H, Nakagawa,K.2015.”Repeated episodes of spontaneous regression/progression of cervical adenocarcinoma after adjuvant chemoradiation therapy: a case report”. J Med Case Rep.9:114.

Kaufmann,M.2009.“On the free energy that drove primordial anabolism.” International journal of molecular sciences vol. 10,4 1853-1871.

Kaufmann,P,Huppertz,B,Frank,HG.1996.”The fibrinoids of the human placenta: origin, composition and functional relevance”.Ann Anat.;178(6):485-501.

Kaufmann,Y,Many,A,Rechavi,G.1995.”Brief report: lymphoma with recurrent cycles of spontaneous remission and relapse--possible role of apoptosis”. N Engl J Med.332(8):507-510.

Keidan,RD,Fanning,J,Gatenby,RA,Weese,JL.1989."Recurrent typhlitis. A disease resulting from aggressive chemotherapy". Diseases of the Colon and Rectum 32 (3): 206–9.

Ken min chin, Chung yip chang,Ser yee lee.1982.”Spontaneous regression of hepatocellular carcinoma”. Gastroenterology 82: 770-774.

Kenny,P,Lee, G,Bissell,M.2007.”Targeting the Tumor Microenvironment”. Frontiers in Bioscience 12: 3468-3474.
Kenny,P,Nelson,C,Bissell, M.2006.”The Ecology of Tumors”. The Scientist 20(4): 31–35.

Kenny,PA, and Mina,JB.2003.“Tumor reversion: correction of malignant behavior by microenvironmental cues”.International journal of cancer vol. 107,5 : 688-95.

Khorana,AA.2010.“Venous thromboembolism and prognosis in cancer”. Thrombosis research vol. 125,6 : 490-3.

Kihara,K,Fujita,S Ohshiro,T,Yamamoto,S,Sekine,S.2015.”Spontaneous regression of colon cancer”. Jpn J Clin Oncol.45(1):111-114.

Kinoshita,T,Kamiyama,I,Hayashi,Y.2015.”Spontaneous Regression of Metastatic Extraskeletal Myxoid Chondrosarcoma”.Ann Thorac Surg. 100(4):1465-1467.

Kitamura,W,Kobayashi,H,Noda,M.2024.”Spontaneous regression of multiple solitary plasmacytoma harboring Epstein-Barr virus: a case report and literature review”. Int J Hematol. 120(1):128-134.

Kitsou,K et al.2021.“Viral Causality of Human Cancer and Potential Roles of Human Endogenous Retroviruses in the Multi-Omics Era: An Evolutionary Epidemiology Review”. Frontiers in oncology vol. 11 687631.

Kitsou,K, Iliopoulou,M, Spoulou,V, Lagiou,P, Magiorkinis,G.2021.”Viral Causality of Human Cancer and Potential Roles of Human Endogenous Retroviruses in the Multi-Omics Era: An Evolutionary Epidemiology Review”. Front Oncol. 11:687631.

Klee,NS, McCarthy,CG, Martinez-Quinones,P, Webb, RC. 2017. “Out of the frying pan and into the fire: damage-associated molecular patterns and cardiovascular toxicity following cancer therapy”.Therapeutic Advances in Cardiovascular Disease 11 (11): 297–317.

Kleef,R,and Dieter Hager,E.2013.”Fever, Pyrogens and Cancer”. In: Madame Curie Bioscience Database [Internet]. Austin (TX): Landes Bioscience;2000-2013.

Kleef,R,Jonas,WB,Knogler,W.2001.”Fever,cancer incidence and spontaneous remissions”. Neuroimmunomodulation 9(2):55–64.

Klitgaard,A,Løkke,A,Lager,J,Rasmussen,TR,Hilberg,O.2022.”Complete Spontaneous Regression of Squamous-Cell Lung Cancer: A Case Report. Case Rep Oncol. 2022;15(2):630-635.

Knelson,EH,Nee,JC,Blobe,GC.2014.”Heparan sulfate signaling in cancer”. Trends Biochem Sci. 39(6):277-288.

Knöfler,M et al.2019.“Human placenta and trophoblast development: key molecular mechanisms and model systems”.Cellular and molecular life sciences : CMLS vol. 76,18 : 3479-3496.

Kondo,S,Okusaka,T,Ueno,H, Ikeda, M, Morizane, C.2006.” Spontaneous regression of hepatocellular carcinoma”. Int J Clin Oncol 11: 407-411.

Kouzis,A.2004.”Cancer according to the Ancient Greek Doctors”.Stamoulis Publications.Athens.31-81.

Krump,NA, and Jianxin,Y.2018.“Molecular mechanisms of viral oncogenesis in humans”. Nature reviews. Microbiology vol. 16,11 : 684-698.

Kovalská,J, Mishra,R, Jebavý,L,Makovický,P, Janda,J.2015.” Tumor progression and spontaneous regression in the lewis rat sarcoma model”. Anticancer Res 35: 6539-6549.

Krutchik,AN,Buzdar,AU,Blumenschein,GR,Lukeman,JM.1978.”Spontaneous regression of breast carcinoma”. Arch Intern Med.138(11):1734-1735.

Kular,JK et al.2014.“The extracellular matrix: Structure, composition, age-related differences, tools for analysis and applications for tissue engineering”. Journal of tissue engineering vol. 5 2041731414557112.

Kumar,T,Patel,N,Talwar,A.2010.”Spontaneous regression of thoracic malignancies”. Respir Med. Oct;104(10):1543– 50.
Kurita,M,Hirano,K,Ebihara,S.2007.”Spontaneous regression of cervical lymph node metastasis in patients with mesopharyngeal squamous cell carcinoma of the tongue: possible association between apoptosis and tumor regression”. Int J Clin Oncol. 12:448–454.
Kwaan,HC,Lindholm,PF.2019.”Fibrin and Fibrinolysis in Cancer.Semin Thromb Hemost. 45(4):413-422.

Kyrgiou,M,Moscicki,AB.2022.”Vaginal microbiome and cervical cancer”. Semin Cancer Biol.86(Pt 3):189-198.

Lambert,AW et al.2017.“Emerging Biological Principles of Metastasis.” Cell vol. 168,4: 670-691.

Lamm,DL.2000.”Efficacy and safety of Bacille Calmette-Guérin immunotherapy in superficial bladder cancer”. Clin Infect Dis. 31:S86-S90.
Lanier,LL,Corliss,BC,Wu,J, Leong,C, Phillips, JH.1998.” Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells”. Nature 391:703–707.
Lanier,LL,Yu ,G, Phillips,JH.1989.” Co-association of CD3 zeta with a receptor (CD16) for IgG Fc on human natural killer cells”. Nature 142:803–805.
Lanier,LL.2003.”Natural killer cell receptor signaling”.Curr Opin Immunol. 15:308–314.
Lapidot , Dar,A, Kollet,O.2005.” How do stem cells find their way home?”. Blood 106(6):1901-1910

Lapidot,T, Dar, A,Kollet,O.2005.”How do stem cells find their way home?”. Blood 106(6):1901-1910.

Larkin, JO et al.2007. "Electrochemotherapy". Annals of Surgery. 245 (3): 469–479.

Lau,KL,Lee,CW,Tustin,H,Stafford,F.2022.”Spontaneous regression of advanced-stage oropharyngeal squamous cell carcinoma”. J Laryngol Otol. 136(9):882-884.

Lawther,AJ et al.2022.“Disrupting circadian rhythms promotes cancer-induced inflammation in mice.” Brain, behavior, & immunity - health vol. 21 100428.

Lederman,GS,Niloff,JM,Redline,R,Rosen,EM.”Late recurrence in endometrial carcinoma”. Cancer 59:825–828.
Lee, MY..2022.“Embryonic Programs in Cancer and Metastasis-Insights From the Mammary Gland”. Frontiers in cell and developmental biology vol. 10 938625.

Lee,JH,Ryu,KW,Kim,S,Bae,JM.2004.”Preoperative plasma fibrinogen levels in gastric cancer patients correlate with extent of tumor”. Hepatogastroenterology 51(60):1860-1863.

Lee,VH,Ng,SC,Leung,TW,Au,GK,Kwong,DL.2012."Dosimetric predictors of radiation-induced acute nausea and vomiting in IMRT for nasopharyngeal cancer".
International Journal of Radiation Oncology, Biology, Physics. 84 (1): 176–182.

Lee,VH,Ng,SC,Leung,TW,Au,GK,Kwong,DL.2012."Dosimetric predictors of radiation-induced acute nausea and vomiting in IMRT for nasopharyngeal cancer". International Journal of Radiation Oncology, Biology, Physics. 84 (1): 176–182.

Lei,KI,Gwi,E,Ma,L,Liang,EY,Johnson,PJ.1997.”Spontaneous' regression of advanced leiomyosarcoma of the urinary bladder”. Oncology 54(1):19-22.

Lema,T,Metin,B,Mehmet,E,Hasan,E,Hatice,T.2005.”Gastric heterotopia together with intestinal metaplasia in the gallbladder: Case report and review of literature”.Turk J Gastroenterol 16 (3): 160-162.

Leshan,L.1977.You Can Fight for Your Life: Emotional Factors in the Causation of Cancer.‎London: UNKNO.

Levin,M.2003.”Bioelectromagnetics in morphogenesis. Bioelectromagnetics. 24(5):295-315.

Levin,M.2012. “Morphogenetic fields in embryogenesis, regeneration, and cancer: non-local control of complex patterning”.Bio Systems vol. 109,3 : 243-61.

León,X,Ferlito,A,Myer,CM.2002.”Second primary tumors in head and neck cancer patients”. Acta Otolaryngol. 122(7):765-778.

Li,AJ,Wu,MC,Cong,WM,Shen,F,Yi,B.2003.”Spontaneous complete necrosis of hepatocellular carcinoma: a case report”. Hepatobiliary Pancreat Dis Int. 2:152–154.
Li,HC et al.2006. “Stem cells and cancer: evidence for bone marrow stem cells in epithelial cancers”.World journal of gastroenterology vol. 12,3 : 363-71.

Liang,J,Huang,Y,Yin,L et al. 2023.”Cancer risk following surgical removal of tonsils and adenoids — a population-based, sibling-controlled cohort study in Sweden”. BMC Med 21,194.

Lifson,S.1997.”On the crucial stages in the origin of animate matter”. J Mol Evol. 44(1):1-8.

Lim,M,Park,S,Jeong,HO.2021.”Circulating Tumor Cell Clusters Are Cloaked with Platelets and Correlate with Poor Prognosis in Unresectable Pancreatic Cancer”.Cancers (Basel) 13(21):5272.

Lima-Junior,DS,Krishnamurthy,SR,Bouladoux,N.2021.”Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota”. Cell 184 (14) :3794-3811.

Lind,MJ.2008. "Principles of cytotoxic chemotherapy". Medicine. 36 (1): 19–23 .

Lipp,M,Koch,E,Brandner,G,Bredt,W.1979.”Simulation and prevention of retrovirus--specific reactions by mycoplasmas”.Med Microbiol Immunol. 167(2):127-136.

Liu,S et al.2017.“Effect of Hypoxia on the Differentiation and the Self-Renewal of Metanephrogenic Mesenchymal Stem Cells”.Stem cells international vol. 2017: 7168687.

Liu,Y and Soper,C.2009. “The Natural History of Retroviruses”. Answers Research Journal vol. 2 : 97–106.

Liu,Z,Zou,JW,Wang,WL,Li,Z.2020.”Spontaneous regression of recurrent hepatocellular carcinoma with multiple lung metastases”.J Cancer Res Ther. 16(7):1710-1713.

Loeb,LA,and Harris,CC.2008.”Advances in chemical carcinogenesis: a historical review and prospective”.Cancer Res.68(17):6863-6872.

Lopez-Pastorini,A, Plönes,T, Brockmann,M, Ludwig,C,Beckers,F Stoelben,E.2015. ”Spontaneous regression of non-small cell lung cancer after biopsy of a mediastinal lymph node metastasis: a case report”. J Med Case Rep. 9:217.

Lu,P et al.2011.“Extracellular matrix degradation and remodeling in development and disease”.Cold Spring Harbor perspectives in biology vol. 3,12 a005058.

Lu,S,Wei,F,Li,G.2021.”The evolution of the concept of stress and the framework of the stress system”. Cell Stress5(6):76-85.

Luzzi,K J et al.1998. “Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases”. The American journal of pathology vol. 153,3: 865-73.

MacIntyre,N.2014.”Tissue Hypoxia: Implications for the Respiratory Clinician”. Respiratory Care October 59 (10) :1590-1596.

Mahmood,SS,and Nohria,A.2016. "Cardiovascular Complications of Cranial and Neck Radiation". Current Treatment Options in Cardiovascular Medicine 18 (7): 45.

Mahooti,S et al.2010.“Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion”. Oncotarget vol. 1,2: 131-147.

Malhotra,V,and Perry,MC.2003.”Classical Chemotherapy: Mechanisms, Toxicities and the Therapeutc Window”. Cancer Biology & Therapy, 2(sup1), 1–3.

Malik,M,Michalak,M,Sigorski,D,Bodnar,L,Lewandowski,T,Nawrocki,S. Spontaneous regression of metastatic renal cell carcinoma after cytoreductive nephrectomy followed by relapse at 3 years.Pol Arch Intern Med. 134(3):16681.

Manos,J.2022.”The human microbiome in disease and pathology”.APMIS. 130(12):690-705.
Markovic,S,Ferlan-Marolt,V,Hlebanja,Z.1996.”Spontaneous regression of hepatocellular carcinoma”. Am J Gastroenterol.91(2):392-393.

Marques,C, Reis,CA, Vivès, RR, Magalhães A. 2021.”Heparan Sulfate Biosynthesis and Sulfation Profiles as Modulators of Cancer Signalling and Progression”. Front Oncol 11:778752.

Martínez-Madrigal,F,Ortiz-Hidalgo,C,Torres-Vega,C.2000.”Cambios regenerativos atípicos, displasia y carcinoma in situ en gastritis crónica asociada con Helicobacter pylori [Atypical regenerative changes, dysplasia, and carcinoma in situ in chronic gastritis associated with Helicobacter pylori]”. Rev Gastroenterol Mex. 65(1):11-17.

Maruo,K,Kayashima,KI,Ono,T.2000.”Regressing merkel cell carcinoma - a case showing replacement of tumor cells by foamy cells”. Br J Dermatol 142: 1184-1189.

Maryanovich,M et al.2018.“Neural Regulation of Bone and Bone Marrow”. Cold Spring Harbor perspectives in medicine vol. 8,9 a031344. 4.

Massberg,S, Schaerli,P, Knezevic-Maramica, I, Köllnberger, M, Tubo, N, Moseman, EA,Huff,IV.2007.”Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues”. Cell 131(5):994-1008.

Massberg,S, Schaerli,P, Knezevic-Maramica,I, Wagers,A, Mazo,I. 2007. ”Immunosurveillance by Hematopoietic Progenitor Cells Trafficking through Blood, Lymph, and Peripheral Tissues”.Cell Vol.131,Issue 5,994-1008.

Massberg,S et al.2007.“Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues”. Cell vol. 131,5 : 994-1008.

Matsuo,R,Ogata,and H,Tsuji,H.2001.”Spontaneous regression of hepatocellular carcinoma--a case report”. Hepatogastroenterology 48 (42):1740-1742.

Maverakis,E,Cornelius,LA,Bowen,GM,Phan,T,Patel,FB,Fitzmaurice,S.2015. "Metastatic melanoma - a review of current and future treatment options". Acta Dermato-Venereologica 95 (5): 516–524.

McDonald,PG et al.2013.“Psychoneuroimmunology and cancer: a decade of discovery, paradigm shifts, and methodological innovations”. Brain, behavior, and immunity vol. 30 Suppl: S1-9.

McGovern,VJ.1975.”Spontaneous regression of melanoma”.Pathology 7(2):91-99.

McKinney-Freeman,S,Jackson,K,Camargo,F,Ferrari,G,Mavillo,F,Goodell, M. 2002. ”Muscle-derived hematopoietic stem cells are hematopoietic in origin”.Proc Natl Acad Sci U.S.A 99(3): 1341–1346.

McLaren, A.1974.” Embryogenesis”. Basic Life Sci.4(PT. B):297-316.

Meckes,DG,and Raab-Traub,N.2011.”Microvesicles and Viral Infection”.J Virol 85: 24.

Meek,AG.1998.”Βreast radiotherapy and lymphedema”.Cancer 83 (12 Suppl American) : 2788–2797.

Melichar,B,Vankov,J,Morvek,P,Urminsk,H,Podhola,M.2009.”Spontaneous regression of renal cell carcinoma lung metastases in a patient with psoriasis”. Vol. 48, Acta Oncologica p. 925–7.
Mende,N et al.2022.“Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.” Blood vol. 139,23 : 3387-3401.

Menon,MP,and Eaton,KD.2015.”Spontaneous regression of non-small-cell lung cancer in AIDS after immune reconstitution”. J Thorac Oncol.10:e1-e2.
Minacapelli,CD.2022.“The Spontaneous Regression of Primary Gastrointestinal Malignancies:An Observational Review”.Cureus vol. 14,12 e32970.

Minchinton,AI,andTannock,IF.2006."Drug penetration in solid tumours". Nature Reviews. Cancer. 6 (8): 583–92.

Mitchell,R, Kaur,A, Munoh Kenne,F, Khan,A, Zafar,W.2021.”Spontaneous Regression of Metastatic Lesions of Adenocarcinoma of the Gastro-Esophageal Junction”. Cureus 13(10):e18784.

Mitterbauer,M,Fritzer-Szekeres,M,Mitterbauer,G.1996.”Spontaneous remission of acute myeloid leukemia after infection and blood transfusion associated with hypergammaglobulinaemia”. Ann Hematol.73(4):189-193.

Modell,H et al.2015.“A physiologist's view of homeostasis.” Advances in physiology education vol. 39,4 : 259-66.

Mohammad,S,Mohammad,SM,Shagufta,P.2019.”A note on mycoplasmal origin of cancer”.The Journal of Medical Research 5(6): 224-226.

Moharil,RB et al.2017.“Cancer stem cells: An insight.” Journal of oral and maxillofacial pathology : JOMFP vol. 21,3 : 463.

Mokhtari,RB et al.2017. "Combination therapy in combating cancer". Oncotarget. 8 (23): 38022–38043.

Monsuez,JJ,Charniot,JC,Vignat,N,Artigou,JY.2010.”Cardiac side-effects of cancer chemotherapy”. Int J Cardiol.144(1):3-15.

Montaudié,H et al.2011."Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity". Journal of the European Academy of Dermatology and Venereology. 25 (Suppl 2): 12–8.

Morigi,A,Casadei,B,Argnani,L,Cavo,M,Zinzani,PL.2019.”Spontaneous remission of follicular lymphoma”. Hematol Oncol.37(5):626-627.

Moschovi,M,Critselis,E,Cen,O,Adamaki,M,Lambrou,GI,Chrousos,GP, Vlahopoulos S.(2015). "Drugs acting on homeostasis: challenging cancer cell adaptation". Expert Review of Anticancer Therapy. 15 (12): 1405–17.

Mozafari,R et al.2017.”Spontaneous complete remission in a patient with acute myeloid leukemia and severe sepsis”.Case Rep Hematol : 9593750.

Munirajan,AK,Ando,K,Mukai,A.2008.”KIF1B functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death”. J Biol Chem.283:24426–24434.
Munro,A, Powell,RG,A Cohen,P.2016.”Spontaneous regression of CIN2 in women aged 18-24 years: a retrospective study of a state-wide population in Western Australia”. Acta Obstet Gynecol Scand. 95(3):291-298.

Munshi,HG,and Stack,MS.2006.”Reciprocal interaction between adhesion receptor signaling and MMP regulation”.Cancer Metastasis Rev.25:45–56.
Muroya,D,Sato,T,Sakai,H,Hisaka,T,Akagi,Y,Okuda,K.2021.”Spontaneous regression of lung metastases in hepatocellular carcinoma: A case report”. Int J Surg Case Rep. 78:378-381.

Murray,JB.1980.”Psychosomatic aspects of cancer: an overview.” J Genet Psychol.136 (2d Half):185-194.

Musso,C,Bezic,J,Christiansen,S,Algranati,L.2007.”Histological Glomerular patterns as chaotic attractors”.Rev Electron Biomed / Electron J Biomed 1:21-27.

Musso,CG.2017.”Histological glomerular patterns as chaotic attractors”.Electron J Biomed 1:21-27.

Méndez-López,LF.2022.“Revisiting Epithelial Carcinogenesis.”International journal of molecular sciences”. vol. 23,13 7437.

Nagorsen,D,Marincola,FM,Kaiser,HE.2002.”Bacteria-related spontaneous and therapeutic remission of human malignancies”. In Vivo.16(6):551-556.

Nagy,JA,Chang, SH,Dvorak,AM, Dvorak,HF.2009.” Why are tumour blood vessels abnormal and why is it important to know?”.Br J Cancer 100(6):865-869.

Nakajima,T,et al.2006.”Spontaneous regression of bone metastasis from renal cell carcinoma; A case report”. BMC Cancer Dec;6(1).
Nakamura,N.2022.“MECHANISMS OF RADIATION CARCINOGENESIS: WHAT IS REALLY INDUCED?.” Radiation protection dosimetry vol. 198,13-15 : 1090-1097.

Nakano,E,Sonoda,T,Fujioka,H,Okuyama,A,Matsuda,M.1984.”Spontaneous regression of pulmonary metastases after nephrectomy for renal cell carcinoma Eur Urol 10: 212-213.

Nakayama,S.2012.”Spontaneous regression of hepatocellular carcinoma”.Indian J Gastroenterol.31(5):267-270.

Navratil,JS,Liu,CC,Ahearn,JM.2006.”Apoptosis and autoimmunity. Immunol Res. 36:3–12.
National Cancer Institute (NIH),USA.2023.https:// www.cancer.gov/ about-cancer/ diagnosis-staging/ diagnosis/tumor-markers-list
Nelson,N,Carnegie,R,Martin,J,Davari,H,Hooley,P,Roden,D,Rowland-Jones,S.2003. ”Demystified.Human endogenous retroviruses”.Molecular pathology 56(1):11–18.

Nesnow,S, Triplett, LL, Slaga,TJ.1983.” Mouse skin tumor initiation-promotion and complete carcinogenesis bioassays: mechanisms and biological activities of emission samples”. Environ Health Perspect. 47:255-268.

Neugut,AI,and Prigerson,HG.2017.“Curative, Life-Extending and Palliative Chemotherapy : New Outcomes Need New Names.” The oncologist vol. 22,8 : 883-885.

Niakan,B.1993.”Steady tumor growth and spontaneous disappearance of cancer”. J Natl Cancer Inst 85: 68-69.

Nicholson,G.W.de P.1950.Studies on Tumour Formation.London:Butterworth & Co.Publishers.

Nogimori,C,Yamamoto,H,Nonaka,K,Sazuka,M,Hamaya,H,Yamada,H.2017.”Spontaneous regression of lung cancer in an elderly patient: A case report”.Nihon Ronen Igakkai Zasshi( Japanese Journal of Geriatrics )54(4):555-559.

Nolte-'t Hoen,E,Cremer,T,Gallo,RC,Margolis,LB.2016.”Extracellular vesicles and viruses: Are they close relatives?”.Proc Natl Acad Sci U S A. 113(33):9155-9161.

Nomura,M,Fujimura,M,Matsuda, T.1994.”Spontaneous regression of small cell lung cancer”. Nihon Kyobu Shikkan Gakkai Zasshi 32(4):324-327.

Nuccitelli,R.1988.”Ionic currents in morphogenesis”.Experientia.44(8):657-666.

Numata,M et al.2021.“Metastasis of Breast Cancer Promoted by Circadian Rhythm Disruption due to Light/Dark Shift and its Prevention by Dietary Quercetin in Mice”.Journal of circadian rhythms vol. 19 2:18.

O'Brien,MER et al.2006.“Mortality within 30 days of chemotherapy: a clinical governance benchmarking issue for oncology patients.” British journal of cancer vol. 95,12 : 1632-6.

Obenauf,AC and Massagué,J.2015. “Surviving at a Distance: Organ-Specific Metastasis”. Trends in cancer vol. 1,1 : 76-91.

Ogawa,R,Watanabe,H,,Yazaki K.2015.”Lung cancer with spontaneous regression of primary and metastatic sites: a case report”. Oncol Lett. 10:550-552.
Ohgi,S,Ehara,S,Satoh,T,Kato,S,Shimosegawa,K,Ishida,Y.2002.“Spontaneous regression of malignant lymphoma of the lumbar spine”. Skeletal Radiol. 31(2):99-102.

Ohsawa,F, Igai,H, Yazawa,T, Matsuura,N, Kamiyoshihara,M. 2021. Kyobu Geka.74 (6):429-433.

Okada,Y,Miyamoto,S,Mimura,T,Ishikawa,T,Sekizawa,A,Matsumoto,K.2019. “Spontaneous regression of quiescent gestational trophoblastic disease after pregnancy: a case report”.BMC Womens Health 19(1):101.

Okamoto,T, Yoshimoto,T, Ohike,N, Fujikawa,A, Kanie,T, Fukuda,K.2021. “Spontaneous regression of gastric gastrinoma after resection of metastases to the lesser omentum: A case report and review of literature”. World J Gastroenterol. 27(1):129-142.

Okamoto,U,Nagamatsu,Y,Amemiya,T.1981.”HumanSpleen Insoluble Fibrinolytic Proteinase Acting at Neutral pH: Its partial putification and characterization”.Thromb Haemost 45(02): 180-185.

Olalde,R and José, A.2005.“The Systemic Theory of Living Systems and Relevance to CAM: Part I: The Theory”. Evidence-based complementary and alternative medicine : eCAM vol. 2,1: 13-18.

Old, LJ. 2007.”Cancer is a Somatic Cell Pregnancy”. Cancer Immun 7: 19-21.

Ooi,KH,Cheo,T,Soon,GST,Leong,CN.2018.”Spontaneous regression of locally advanced nonsmall cell lung cancer:A case report”.Medicine(Baltimore). 97(31):e11291.

Otsuka,K,and Iwasaki,T.2023.”Insights into radiation carcinogenesis based on dose-rate effects in tissue stem cells”. Int J Radiat Biol.99(10):1503-1521.

Ottosen,LD,Hindkaer,J,Husth,M,Petersen,DE,Kirk,J,Ingerslev,HJ.2006.”Observations on intrauterine oxygen tension measured by fibre-optic microsensors”. Reprod Biomed Online 13(3):380-385.

Ouyang,Y et al.2021.“Trophoblastic extracellular vesicles and viruses: Friends or foes?”. American journal of reproductive immunology vol. 85,2 : e13345.

Oviedo,NJ, and Beane,WS.2009.“Regeneration: The origin of cancer or a possible cure?”. Seminars in cell & developmental biology vol. 20,5: 557-64.

Ozden,I,Dizdaroğlu,F,Poyanli,A,Emre,A.2005.”Spontaneous regression of a pancreatic head mass and biliary obstruction due to autoimmune pancreatitis”. Pancreatology 5(2-3):300-303.

Pack,GT.1967.”St. Peregrine, O.S.M.--the patron saint of cancer patients”. Can Med Assoc J.17:181-182.
Pan,SY et al.2022.“Synchronous/Metachronous Multiple Primary Malignancies: Review of Associated Risk Factors.” Diagnostics (Basel, Switzerland) vol. 12,8 1940.

Pang,C,Sharma,D,Sankar,T.2015.”Spontaneous regression of merkel cell carcinoma: A case report and review of the literature”. Int J Surg Case Rep 7: 104-108.

Park,H et al.2018.”Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms”.Nat Commun.:9 (1):5293.

Park,JY.2019.”Second Primary Cancer after Treating Gastrointestinal Cancer”. Korean J Gastroenterol.74(4):193-196.

Park,TS et al.2014.“Dynamic Interactions Between Cancer Stem Cells And Their Stromal Partners”. Current pathobiology reports vol. 2,1: 41-52.

Park,YH, Park, BM, Park, SY.2016.”Spontaneous regression in advanced squamous cell lung carcinoma”. J Thorac Dis.8(3):E235-E239.

Park,WW,and Corkhill,JW.1980.The Histology of Borderline Cancer.Berlin Heidelberg New York:Springer-Verlag.

Parker,WB.2009.“Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer”.Chemical reviews vol. 109,7: 2880-93.

Parker,MC,and Jeynes,C.2019.“Maximum Entropy(Most Likely)Double Helical and Double Logarithmic Spiral Trajectories in Space-Time”.Sci Rep, vol. 9, no. 1, p. 10779.

Pasvolsky,O,Berger,T,Bernstine,H,Hayman,L,Raanani,P,Vidal,L.2019.“Spontaneous Regression of Hodgkin Lymphoma: Case Report and Review of the Literature”. Acta Haematol. 141(1):14-18.

Paterlini-Bréchot,P.2014.“Circulating Tumor Cells: Who is the Killer?”. Cancer microenvironment:official journal of the International Cancer Microenvironment Society vol. 7,3 : 161-76.

Peddareddigari,VG et al.2010.“The tumor microenvironment in colorectal carcinogenesis”.Cancer microenvironment : official journal of the International Cancer Microenvironment Society vol. 3,1 149-66.

Pensotti,A,Bertolaso,M,Bizzarri,M.2023.”Is Cancer Reversible?Rethinking Carcinogenesis Models- A New Epistemological Tool”.Biomolecules 13(5):733.

Pensotti,A et al.2024.“The phenotypic reversion of cancer: Experimental evidences on cancer reversibility through epigenetic mechanisms (Review)”. Oncology reports vol. 51,3: 48.

Pickup,M et al.2014.“The extracellular matrix modulates the hallmarks of cancer”. EMBO reports vol. 15,12: 1243-53.

Pillwein,K,Jayaram,HN, Wever, G.1986.” Die Biochemie der Krebszelle. Purin- und Pyrimidinstoffwechsel [The biochemistry of the cancer cell. Purine and pyrimidine metabolism]”. Padiatr Padol.21(4):323-334.

Piñeiro,R,Martínez-Pena,I,López-López,R.2020.”Relevance of CTC Clusters in Breast Cancer Metastasis”. Adv Exp Med Biol.1220:93-115.

Plochmann,G.1953.”D'Arcy Thompson:His Conception of the Living Body”. Philosophy of Science Vol. 20, No. 2 : pp. 139-148.

Pollack,JD.1997.”Mycoplasma genes: a case for reflective annotation”.Trends Microbiol.5(10):413-419.

Porter,C,Shrestha,E,Peiffer,LB,Sfanos,KS.2018.”The microbiome in prostate inflammation and prostate cancer”.Prostate Cancer Prostatic Dis. 21(3):345-354.

Prehn,R.2017.”Regeneration versus neoplastic growth”.Carcinogenesis 18 (8):1439-1444.


Printz,C.2001.”Spontaneous regression of melanoma may offer insight into cancer immunology”.J Natl Cancer Inst. 93:1047–1048.
Prokop,A.2021.“Towards the First Principles in Biology and Cancer: New Vistas in Computational Systems Biology of Cancer”.Life (Basel, Switzerland) vol. 12,1: 21.

Prokopenko,M.2009.“Guided self-organization”. HFSP journal vol. 3,5 : 287-9.

Pross,A.2003.”The driving force for life's emergence: kinetic and thermodynamic considerations". J Theor Biol.220(3):393-406.

Qiao,K, Han,J,Zhang H.2023. Intratumor Mycoplasma promotes the initiation and progression of hepatocellular carcinoma. Cell Rep.42(12):113563.

Qin,LZ,Zhou,J,Hu,L,Wang,SL.2023.”Zhonghua Kou Qiang Yi Xue Za Zhi. (Homeostatic medicine: new strategy and concept of health maintenance as well as diagnosis and treatment of diseases)”.58(2):109-117.

Quail,DF, and Joyce,JA.2013.”Microenvironmental regulation of tumor progression and metastasis”.Nat Med.19(11):1423-1437.

Rachel Airley.2009. Cancer chemotherapy. Wiley-Blackwell.

Rademacher,TW,Parekh,RB,Dwek,RA.1988.”Glycobiology”.Ann Rev Biochem 57 :785-838.

Radford,JA, Ryder, DJ, Dodwell,D, Anderson,H, Thatcher,N.1993.”Predicting septic complications of chemotherapy: An analysis of 382 patients treated for small cell lung cancer without dose reduction after major sepsis”. Eur J Cancer 29A(1): 81–86.

Raishan,S,Alsabri,M,Hanna,AM,Brett,M.2019.”Resolution of pituitary microadenoma after coronavirus disease 2019 : a case report”. J Med Case Rep.15 (1):544.

Rajman,L,Chwalek, K, Sinclair,DA.2018. "Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence". Cell Metabolism. 27 (3): 529–547.

Rangel,L(ed).2013.Cancer Treatment -Conventional and Innovative Approaches. Vitoria,Brazil: Federal University of Espirito Santo.

Rashidi,A,and Fisher,SI.2015.”Spontaneous remission of acute myeloid leukemia. Leuk Lymphoma”.56(6):1727-1734.

Razin,S et al.1998.“Molecular biology and pathogenicity of mycoplasmas”. Microbiology and molecular biology reviews : MMBR vol. 62,4: 1094-156.

Rebollo,J,Llorente,I,Yoldi,A.1990.”Regresión tumoral espontánea en un paciente con cáncer gástrico metastásico. Communicación de un caso adicional [Spontaneous tumor regression in a patient with metastatic gastric cancer. Communication of an additional case]”. Rev Med Univ Navarra 34(3):141-142.

Reed,JC.1996.”Balancing cell life and death.Bax, apoptosis, and breast cancer”. J Clin Invest.97:2403–2404.
Rejniak,KA.2016. “Circulating Tumor Cells: When a Solid Tumor Meets a Fluid Microenvironment”. Advances in experimental medicine and biology vol. 936 : 93-106.

Reyngold,M,Parikh,P,Crane,CH.2019."Ablative radiation therapy for locally advanced pancreatic cancer: techniques and results". Radiation Oncology. 14 (1): 95.

Ricard,J.2003.”What do we mean by biological complexity?”.C R Biol. 326(2):133-140.

Riggio,AI,Varley,KE,Welm,AL.2021.”The lingering mysteries of metastatic recurrence in breast cancer”. Br J Cancer. 124(1):13-26.

Roberts,RM et al.2016.“The evolution of the placenta.”Reproduction (Cambridge, England) vol. 152,5 (2016): R179-89.

Rogers,MB.2011.”Mycoplasma and cancer: in search of the link.” Oncotarget 2: 271-273.

Rohen,J.1979.”Functional Systems-A New Concept for the Structural Organization of the Human Body”.In the “A New Image of Man in Medicine” Vol II ,Basis of an Individual Physiology.New York, Futura Publishing Company,1-14.

Ross,MB,Buzdar,AU,Hortobagyi,GN,Lukeman,JM.1982.”Spontaneous regression of breast carcinoma: follow-up report and literature review”. J Surg Oncol.19(1):22-24.

Rossi,E,Vita,A, Baccetti S, Di Stefano M, Voller F, Zanobini A.2015. Complementary and alternative medicine for cancer patients: results of the EPAAC survey on integrative oncology centres in Europe.Support Care Cancer 23(6):1795-1806.

Rowinsky,EK,and Donehower,RC.1991."The clinical pharmacology and use of antimicrotubule agents in cancer chemotherapeutics". Pharmacology & Therapeutics. 52 (1): 35–84.

Rozario,T,and DeSimone,DW.2010. “The extracellular matrix in development and morphogenesis: a dynamic view”.Developmental biology vol. 341,1 : 126-40.

Russel,A.1879.Haeckel’s “The Evolution of Man.The Alfred Russel Wallace Page .Kentucky: WKU (Western Kentucky University).https:/ /www.wku.edu /its/websites/people/

Rybak,LP,Mukherjea,D,Jajoo,S,Ramkumar,V.2009."Cisplatin ototoxicity and protection: clinical and experimental studies". The Tohoku Journal of Experimental Medicine. 219 (3): 177–86.

Rønnov-Jessen,L,and Bissell,M.2009.”Breast Cancer by Proxy: Can the Microenvironment be Both the Cause and Consequence?”. Trends Mol Med 5: 5–13.

Sabater, B.2022.“Entropy Perspectives of Molecular and Evolutionary Biology.” International journal of molecular sciences vol. 23,8 4098.

Sait,SF, Danzer,E, Ramirez,D, LaQuaglia,MP, Paul,M. 2018. ”Spontaneous Regression in a Patient With Infantile Fibrosarcoma”.J Pediatr Hematol Oncol. 40(4):e253-e255.

Sasisekharan,R,Shriver,Z,Venkataraman,G,Narayanasami,U.2002.”Roles of heparan - sulphate glycosaminoglycans in cancer”. Nat Rev Cancer. 2(7):521-528.

Schipper,H,Goh,CR,Wang,TL.1995.”Shifting the cancer paradigm: Must we kill to cure? (editorial)”. J Clin Oncol. 13(4):801–7.

Schlabe,J,Shah,KA,Sheerin,F,Payne,MJ,Fasanmade,AA.2018.”Complete spontaneous regression of a metastatic melanoma of the mandible: a case report and follow-up recommendations”.Int J Oral Maxillofac Surg. 47(12):1519-1522.

Schmidt,KL.1910.”Krebs und Infektionskrankheiten”.Med Klinik. 43:1690–1693.

Schuster,E et al.2021.“Better together: circulating tumor cell clustering in metastatic cancer”.Trends in cancer vol. 7,11 : 1020-1032.

Schwartz,L,Devin,A,Bouillaud,F,Henry,M.2020.”Entropy as the driving force of pathogenesis: an attempt of classification of the diseases based on the laws of physics”.Substantia 4(2): 7-13.

Seely,AJE.2020.”Optimizing Our Patients' Entropy Production as Therapy? Hypotheses Originating from the Physics of Physiology”. Entropy (Basel).22 (10):1095.

Sekhon,SS,and Roy,V.2006."Thrombocytopenia in adults: A practical approach to evaluation and management". Southern Medical Journal 99 (5): 491–8, quiz 499–500, 533.

Sekine,A,Oda,T, Shintani,R.2021.”Spontaneous regression following endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer patients”. Respir Investig. 59(5):691-694.

Sesso A,Yamashiro-Kanashiro EH, Arruda LB, Kawakami J, Higuchi ML, Orii NM, Taniwaki NN .2017.”Bacteria arise at the border of mycoplasma-infected HeLa cells, containing cytoplasm with either malformed cytosol, mitochondria and endoplasmic reticulum or tightly adjoined smooth vacuoles”. Rev Inst Med Trop Sao Paulo 59: 1-17.

Shahbazi,MN.2020. “Mechanisms of human embryo development: from cell fate to tissue shape and back.” Development (Cambridge, England) vol. 147,14 dev190629.

Shaikh,AY,and Shih,JA.2012."Chemotherapy-induced cardiotoxicity".Current Heart Failure Reports 9 (2): 117–27.

Shannon,VR.2019."Cancer Treatment-Related Lung Injury". Oncologic Critical Care. pp. 531–556.

Sharma,NK et al.2019.“Mitochondrial Degeneration and Autophagy Associated With Delayed Effects of Radiation in the Mouse Brain”. Frontiers in aging neuroscience vol. 11 357.

Shatola,A, Nguyen,KN, Kamangar,E, Daly,ME.2020.Spontaneous Regression of Non-small Cell Lung Cancer: A Case Report and Literature Review. Cureus. 12(1):e6639.
Shi,J,O et al.2024.”The Uptake of Heparanase into Mast Cells Is Regulated by Its Enzymatic Activity to Degrade Heparan Sulfate”. Int J Mol Sci.25(11):6281.

Shields,LBE,and Rezazadeh,KA.2020.”Spontaneous Regression of Delayed Pulmonary and Mediastinal Metastases from Clear Cell Renal Cell Carcinoma. Case Rep Oncol. 13(3):1285-1294.

Shimizu,H, Kochi,M, Kaiga,T, Mihara,Y, Fujii,M, Takayama,T.2010.” A case of spontaneous regression of advanced colon cancer”. Anticancer Res. 30(6):2351-2353.

Siddik,ZH.2005."Mechanisms of Action of Cancer Chemotherapeutic Agents: DNA-Interactive Alkylating Agents and Antitumour Platinum-Based Drugs".The Cancer Handbook. John Wiley & Sons, Ltd.

Simon,M,Celeste,Keith,B.2008.“The role of oxygen availability in embryonic development and stem cell function”. Nature reviews. Molecular cell biology vol. 9,4 : 285-96.

Simpson-Haidaris,PJ and Rydarczyk,B.2001.”Tumors and Fibrinogen The Role of Fibrinogen as an Extracellular Matrix Protein”.Annals of the New York Academy of Sciences Volume 936,Issue 1 Pages xi-xii, 1-642.

Simpson-Haidaris,PJ and Rybarczyk,B.2001.”Tumors and fibrinogen. The role of fibrinogen as an extracellular matrix protein”.Ann N Y Acad Sci. 936:406-425.

Singh,N et al.2019.“Inflammation and cancer”.Annals of African medicine vol. 18,3: 121-126.

Sipaul,F,Ling,B,Mason,C,Keast,A.2015.”Spontaneous regression of laryngeal squamous cell carcinoma”.J Laryngol<